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KMID : 0366220050400030183
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Korean Journal of Hematology
2005 Volume.40 No. 3 p.183 ~ p.187
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A Case of Acquired Glanzmann’s Thrombasthenia
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Oh So-Yeun
Jang Moon-Ju
Kang Myung-Seo
Oh Do-yeun
Chong So-Young
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Abstract
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Glanzmann’s thrombasthenia (GT) is a rare inherited platelet disorder, which is characterized by a complete lack of platelet aggregation due to a deficiency or abnormality of the membrane glycoprotein IIb/IIIa complex. Anti-GPIIb/IIIa antibodies have also been identified to cause platelet dysfunction in patients with a normal platelet count, but this has only been rarely encountered. The condition is also known as acquired GT. Herein, we describe a patient with acquired GT and a history of Evans’ syndrome, who presented with severe bleeding and platelet dysfunction, but with a normal platelet count and GP IIb/IIIa expression.
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KEYWORD
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Acquired Thrombasthenia, Evans’ syndrome, Platelet aggregation
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